Print Email Facebook Twitter Biocatalytic Oxidation Reactions Title Biocatalytic Oxidation Reactions: A Chemist's Perspective Author Dong, J. (TU Delft BT/Biocatalysis) Fernandez Fueyo, E. (TU Delft BN/Greg Bokinsky Lab) Hollmann, F. (TU Delft BT/Biocatalysis) Paul, C.E. (TU Delft BT/Biocatalysis) Pesic, M. (TU Delft BT/Biocatalysis) Schmidt, S. (TU Delft BT/Biocatalysis) Wang, Yonghua (South China University of Technology) Younes, S.H.H. (TU Delft BT/Biocatalysis) Zhang, W. (TU Delft BT/Biocatalysis) Date 2018 Abstract Oxidation chemistry using enzymes is approaching maturity and practical applicability in organic synthesis. Oxidoreductases (enzymes catalysing redox reactions) enable chemists to perform highly selective and efficient transformations ranging from simple alcohol oxidations to stereoselective halogenations of non‐activated C−H bonds. For many of these reactions, no “classical” chemical counterpart is known. Hence oxidoreductases open up shorter synthesis routes based on a more direct access to the target products. The generally very mild reaction conditions may also reduce the environmental impact of biocatalytic reactions compared to classical counterparts. In this Review, we critically summarise the most important recent developments in the field of biocatalytic oxidation chemistry and identify the most pressing bottlenecks as well as promising solutions. Subject German Edition :D OI:10.1002/ange.201800343 Bioc atalys is International Edition :DOI:10.1002/anie.201800343 Biocatalytic Oxidation Reactions :AChemist s Perspectiv e JiaJia Dong ,Elena Fern μ ndez-Fueyo ,Frank Hollmann,* Caroline E. Paul, Milja Pesic,Sandy Schmidt, Yonghua Wang,Sabry Younes,and Baeyer–Villiger oxidationbiocatalysishalogenationoxidationoxyfunctionalisation To reference this document use: http://resolver.tudelft.nl/uuid:09808c27-e933-4cf3-8629-a0bd66f404ea DOI https://doi.org/10.1002/anie.201800343 ISSN 1433-7851 Source Angewandte Chemie (International Edition), 57 (30), 9238-9261 Part of collection Institutional Repository Document type journal article Rights © 2018 J. Dong, E. Fernandez Fueyo, F. Hollmann, C.E. Paul, M. Pesic, S. Schmidt, Yonghua Wang, S.H.H. Younes, W. Zhang Files PDF Dong_et_al_2018_Angewandt ... dition.pdf 8.16 MB Close viewer /islandora/object/uuid:09808c27-e933-4cf3-8629-a0bd66f404ea/datastream/OBJ/view