Silicon based device for smart assessment of cellular stiffness

Title

Silicon based device for smart assessment of cellular stiffness

 Author

Kawasaki, Shinnosuke (TU Delft Electrical Engineering, Mathematics and Computer Science)

Contributor

Dekker, Ronald (mentor)
Kluba, Marta (mentor)

Degree granting institution

Delft University of Technology

 Programme

Electrical Engineering | Microelectronics

 Date

2017-11-07

 Abstract

Cellular stiffness plays an important role for several diseases such as atherosclerosis, malaria and cancer. Cellular stiffness can be derived by the velocity of a cell that is squeezed through a constriction channel. For example, a rigid cell will move slowly through the constriction channel and vice versa. In this research a microfluidic device with integrated electrodes was fabricated to detect the cell within the constriction channel. The velocity of the cell can be measured if the cell is detected at two different location. In this thesis the fabrication process of the device based on standard IC process is presented and electrically characterized.

 Subject

Cell stiffness
silicon based electrode
standard IC based fabrication

 To reference this document use:

http://resolver.tudelft.nl/uuid:0bdf5c45-20dc-49db-a68f-e943842c60f2

 Embargo date

2019-11-07

 Part of collection

Student theses

 Document type

master thesis

 Rights

© 2017 Shinnosuke Kawasaki
Files
PDF Silicon_based_microfluidi ... ffness.pdf 15.45 MB
Close viewer