Print Email Facebook Twitter Crossing Total Occlusions using a hydraulic pressure wave Title Crossing Total Occlusions using a hydraulic pressure wave: A feasibility study Author Sakes, A. (TU Delft Medical Instruments & Bio-Inspired Technology) Nicolaï, Tjibbe (Student TU Delft) Karapanagiotis, Jordan (Student TU Delft) Breedveld, P. (TU Delft Medical Instruments & Bio-Inspired Technology) Spronck, J.W. (TU Delft Mechatronic Systems Design) Date 2018 Abstract Crossing highly calcified occlusions is technically challenging mainly due to guidewire buckling. In an effort to prevent buckling, a catheter that uses a dynamic impulse load is proposed. The proposed Wave catheter consists of an input plunger to generate an impulse at the handle, a hydraulic pressure wave confined within a ∅2 mm catheter to transfer the impulse towards the tip, and an output plunger to transfer the impulse to the occlusion. To determine the feasibility of this catheter, an experiment was performed in which the input and output impulses were recorded as a function of the catheter type, curvature, and plunger travel distance. Additionally, the system was tested on artificial CTO models to determine the clinical validity. The catheter has illustrated the ability to safely transfer high-force impulses of up to 43 N (1.5 N required) with only minimum catheter type and no curvature dependency, allowing for delivering high-force impulses through tortuous vasculature and under any angle. Furthermore, the catheter was able to penetrate the artificial CTO models within 1 strike. Subject chronic total occlusionshydraulic pressure waveimpulse crossingmedical device designpercutaneous coronary interventions To reference this document use: http://resolver.tudelft.nl/uuid:0c589702-da00-4083-a747-b1fc7b172c11 DOI https://doi.org/10.1088/2057-1976/aad44a Embargo date 2019-08-20 ISSN 2057-1976 Source Biomedical Physics & Engineering Express, 4 (5) Bibliographical note Accepted Author Manuscript Part of collection Institutional Repository Document type journal article Rights © 2018 A. Sakes, Tjibbe Nicolaï, Jordan Karapanagiotis, P. Breedveld, J.W. Spronck Files PDF BPEX_Feasibility_Pressure ... ndices.pdf 8.17 MB Close viewer /islandora/object/uuid:0c589702-da00-4083-a747-b1fc7b172c11/datastream/OBJ/view