Print Email Facebook Twitter Rationally designed meta-implants: a combination of auxetic and conventional meta-biomaterials Title Rationally designed meta-implants: a combination of auxetic and conventional meta-biomaterials Author Kolken, H.M.A. (TU Delft Biomaterials & Tissue Biomechanics) Janbaz, S. (TU Delft Biomaterials & Tissue Biomechanics) Leeflang, M.A. (TU Delft Biomaterials & Tissue Biomechanics) Lietaert, K. (3D Systems – LayerWise NV) Weinans, Harrie (TU Delft Biomaterials & Tissue Biomechanics; University Medical Center Utrecht) Zadpoor, A.A. (TU Delft Biomaterials & Tissue Biomechanics) Date 2018 Abstract Rationally designed meta-biomaterials present unprecedented combinations of mechanical, mass transport, and biological properties favorable for tissue regeneration. Here we introduce hybrid meta-biomaterials with rationally-distributed values of negative (auxetic) and positive Poisson’s ratios, and use them to design meta-implants that unlike conventional implants do not retract from the bone under biomechanical loading. We rationally design and additively manufacture six different types of meta-biomaterials (three auxetic and three conventional), which then serve as the parent materials to six hybrid meta-biomaterials (with or without transitional regions). Both single and hybrid meta-biomaterials are mechanically tested to reveal their full-field strain distribution by digital image correlation. The best-performing hybrid metabiomaterials are then selected for the design of meta-implants (hip stems), which are tested under simulated-implantation conditions.Full-field strain measurements clearly show that, under biomechanical loading, hybrid meta-implants press onto the bone on both the medial and lateral sides, thereby improving implant–bone contact and potentially implant longevity. To reference this document use: http://resolver.tudelft.nl/uuid:2479280e-98d8-4681-b3cb-fb194908ddff DOI https://doi.org/10.1039/C7MH00699C ISSN 2051-6355 Source Materials Horizons, 5 (1), 28-35 Part of collection Institutional Repository Document type journal article Rights © 2018 H.M.A. Kolken, S. Janbaz, M.A. Leeflang, K. Lietaert, Harrie Weinans, A.A. Zadpoor Files PDF c7mh00699c.pdf 4.55 MB Close viewer /islandora/object/uuid:2479280e-98d8-4681-b3cb-fb194908ddff/datastream/OBJ/view