Fusion of CTA and XA data using 3D centerline registration to aid coronary intervention

Coronary Artery Disease (CAD) is one of the most commonly occurring heart diseases worldwide. It results from the buildup of plaque below the intima layer inside the vessel wall of the coronary arteries. This obstruction in the vessel walls hinders the blood flow to the heart muscle.The most commonly used treatment techniques for CAD is Percutaneous Coronary Intervention (PCI). X-ray imaging used during PCI only visualizes lumen of the vessels and gives very less information on stenosis or plaque type. In order to circumvent this problem, preoperative coronary Computed Tomography Angiography (CTA) images may be combined with intraoperative X-ray images. CTA gives valuable information about not only the lumen but also the plaque in the coronary vessels which is not visible on the X-ray images. This project involves registration of 3D centerlines extracted from CTA and XA biplane images. Various point set registration methods are investigated and compared. Next, plaque information extracted from CTA is projected onto XA biplane images using the registration method that yields the best results. Finally, the development of a graphical user interface (GUI) is done in order to automate the registration and visualization process.

Subject

Coronary Artery
CTA
Plaque
Registration
X-ray

To reference this document use:

http://resolver.tudelft.nl/uuid:36434450-c22d-4535-aa35-a5d8860b6d73

Part of collection

Student theses

Document type

master thesis

Rights

Files

PDF

GauravKaila_MScThesis.pdf

4.21 MB

Close viewer