Print Email Facebook Twitter Nanofabricated structures and microfluidic devices for bacteria Title Nanofabricated structures and microfluidic devices for bacteria: From techniques to biology Author Wu, F. (TU Delft BN/Cees Dekker Lab; Kavli institute of nanoscience Delft) Dekker, C. (TU Delft BN/Cees Dekker Lab; Kavli institute of nanoscience Delft) Date 2016 Abstract Nanofabricated structures and microfluidic technologies are increasingly being used to study bacteria because of their precise spatial and temporal control. They have facilitated studying many long-standing questions regarding growth, chemotaxis and cell-fate switching, and opened up new areas such as probing the effect of boundary geometries on the subcellular structure and social behavior of bacteria. We review the use of nano/microfabricated structures that spatially separate bacteria for quantitative analyses and that provide topological constraints on their growth and chemical communications. These approaches are becoming modular and broadly applicable, and show a strong potential for dissecting the complex life of bacteria at various scales and engineering synthetic microbial societies. To reference this document use: http://resolver.tudelft.nl/uuid:396dab4b-a568-4a86-8da7-3cf12b0b9f68 DOI https://doi.org/10.1039/c5cs00514k Embargo date 2017-01-21 ISSN 0306-0012 Source Chemical Society Reviews, 45 (2), 268-280 Bibliographical note Accepted Author Manuscript Part of collection Institutional Repository Document type review Rights © 2016 F. Wu, C. Dekker Files PDF C5CS00514K.pdf 2.58 MB Close viewer /islandora/object/uuid:396dab4b-a568-4a86-8da7-3cf12b0b9f68/datastream/OBJ/view