Novel genome alteration system for microorganisms

Title

Novel genome alteration system for microorganisms

 Author

Daran, J.G.
Geertman, J.M.
Bolat, I.

Faculty

Applied Sciences

 Department

BT/Biotechnology

 Date

2015-06-11

 Abstract

The invention relates to a set of targeting constructs, comprising a first construct comprising a recognition site for an endonuclease, a first region of homology with a target gene of a microorganism, and a first part of a selection marker, and a second construct comprising a second part of the selection marker, a second region of homology with the target gene of the microorganism, and a copy of the endonuclease recognition site. The invention further relates to methods for altering a target gene in a microorganism, to methods for producing a microorganism, and to microorganisms that are produced by the methods of the invention.

 To reference this document use:

http://resolver.tudelft.nl/uuid:3bfbfd5b-2bba-4923-8a27-b875409dd95d

 Publisher

European Patent Office

 Source

http://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=16&ND=3&adjacent=true&locale=en_EP&FT=D&date=20150611&CC=WO&NR=2015084178A1&KC=A1

 Source

WO 2015084178 (A1)

 Part of collection

Institutional Repository

 Document type

patent

 Rights

(c) 2015 The Author(s)
Files
PDF WO2015084178A1.pdf 2.31 MB
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