In vivo multicell inferior olivary recordings

In vivo multicell inferior olivary recordings: alternative design methods for creating cheap and flexible electrode structures

Kerpels, J.J.

Serdijn, W.A. (mentor)

Electrical Engineering, Mathematics and Computer Science

Microelectronics

2016-08-26

In order to allow neuroscientists to do in vivo recordings on hard to reach brain tissue, such as the inferior olivary complex, specially designed electrodes are required. Although a variety of electrodes are commercially available, they are usually expensive and it is hard to rapid prototype new designs. This thesis describes the design process of three electrode array designs, each improved based on the findings of the previous one. The first design was made using a FlexPCB production technique, on which gold spots were added to create conducting measuring sites. The second design combined this technique with commercial microwire electrodes. The third design used 3D print technology combined with microwire electrodes to create an electrode array. All designs were tested in in vivo measurements on mice. Successful measurements were carried out with the electrodes and the new production methods were found to be effective. Using a 3D printer to create electrodes makes for a very flexible design process and can be used to create very specific electrode shapes very rapidly and cost effective.

http://resolver.tudelft.nl/uuid:4ec866c9-3604-45cc-80f6-0e6ee174eb08

Student theses

master thesis

(c) 2016 Kerpels, J.J.