A tomographic UV-sheet scanning technique for producing 3D fluorescence images of x-ray beams in a radio-fluorogenic gel

A tomographic UV-sheet scanning technique for producing 3D fluorescence images of x-ray beams in a radio-fluorogenic gel

Yao, T. (TU Delft RST/Applied Radiation & Isotopes)
Gasparini, A. (TU Delft RST/Applied Radiation & Isotopes)
de Haas, M.P. (TU Delft RST/Applied Radiation & Isotopes)
Luthjens, L.H. (TU Delft RST/Applied Radiation & Isotopes)
Denkova, A.G. (TU Delft RST/Applied Radiation & Isotopes)
Warman, J.M. (TU Delft RST/Applied Radiation & Isotopes)

2017-04-11

In this work a 40 mm cube of an optically clear, radio-fluorogenic gel composed of partially-polymerized tertiary-butyl acrylate and maleimido-pyrene (~0.01%) is irradiated with orthogonally-crossed, 10 mm square and round, 200 kVp x-ray beams. A thin sheet of UV light is produced between two parallel plates with 2 mm slits illuminated by collimated, linear-array, LED sources. The gel is transported 1 mm at a time through the UV sheet and the fluorescence from the emissive, polymeric radiolytic product formed in the x-ray tracks is recorded, as both JPEG and raw-DNG files, using a CCD camera placed orthogonal to the plane of the excitation light. The resulting stack of 40 tomographic slices are imported into freely-available software to produce 3D animated images of the radiation-induced fluorescence.

http://resolver.tudelft.nl/uuid:8463a0df-b9a0-4dfd-ae7d-cdf77ef166ab

https://doi.org/10.1088/2057-1976/aa684b

2057-1976

Biomedical Physics & Engineering Express, 3 (2)

Institutional Repository

journal article

© 2017 T. Yao, A. Gasparini, M.P. de Haas, L.H. Luthjens, A.G. Denkova, J.M. Warman