Print Email Facebook Twitter Interactions between model inclusions on closed lipid bilayer membranes Title Interactions between model inclusions on closed lipid bilayer membranes Author Idema, T. (TU Delft BN/Timon Idema Lab; Kavli institute of nanoscience Delft) Kraft, Daniela J. (Universiteit Leiden) Date 2019 Abstract Protein inclusions in the membranes of living cells interact via the deformations they impose on that membrane. Such membrane-mediated interactions lead to sorting and self-assembly of the inclusions, as well as to membrane remodelling, crucial for many biological processes. For the past decades, theory, numerical calculations and experiments have been using simplified models for proteins to gain quantitative insights into their behaviour. Despite challenges arising from nonlinearities in the equations, the multiple length scales involved and the nonadditive nature of the interactions, recent progress now enables for the first time a direct comparison between theoretical and numerical predictions and experiments. We review the current knowledge on the biologically most relevant case, inclusions on lipid membranes with a closed surface and discuss challenges and opportunities for further progress. Subject Analytical modelsCoarse-grained modelsColloidal model systemsDNA origami inclusionsMembrane-mediated interactionsMembrane-protein couplingSelf-assembly To reference this document use: http://resolver.tudelft.nl/uuid:869d9202-efcf-4554-b7b5-7fed39962b7c DOI https://doi.org/10.1016/j.cocis.2019.01.006 Embargo date 2021-01-19 ISSN 1359-0294 Source Current Opinion in Colloid & Interface Science, 40, 58-69 Bibliographical note Accepted Author Manuscript Part of collection Institutional Repository Document type review Rights © 2019 T. Idema, Daniela J. Kraft Files PDF document.pdf 5.92 MB Close viewer /islandora/object/uuid:869d9202-efcf-4554-b7b5-7fed39962b7c/datastream/OBJ/view