Print Email Facebook Twitter Cryogenic transmission electron microscopy Title Cryogenic transmission electron microscopy: the technique of choice for the characterization of polymeric nanocarriers Author Laan, A.C. (TU Delft RST/Applied Radiation & Isotopes) Denkova, A.G. (TU Delft RST/Applied Radiation & Isotopes) Date 2017 Abstract This letter is meant to make scientists aware of the proper application of transmission electron microscopy (TEM) for the assessment of polymeric self-assemblies. Cryogenic (cryo)-TEM should be the method of choice. Here, we show the difference in morphologies observed in the same sample when using cryo-TEM and when using TEM with drying, demonstrating the importance of choosing the proper method. Subject OA-Fund TU Delft To reference this document use: http://resolver.tudelft.nl/uuid:8788e892-c180-4eb0-903b-b458133718f8 DOI https://doi.org/10.1186/s13550-017-0290-3 Source EJNMMI Research, 7 (1) Part of collection Institutional Repository Document type journal article Rights © 2017 A.C. Laan, A.G. Denkova Files PDF s13550_017_0290_3.pdf 581.66 KB Close viewer /islandora/object/uuid:8788e892-c180-4eb0-903b-b458133718f8/datastream/OBJ/view