Print Email Facebook Twitter Catching DNA with hoops-biophysical approaches to clarify the mechanism of SMC proteins Title Catching DNA with hoops-biophysical approaches to clarify the mechanism of SMC proteins Author Eeftens, J.M. (TU Delft BN/Cees Dekker Lab; Kavli institute of nanoscience Delft) Dekker, C. (TU Delft BN/Cees Dekker Lab; Kavli institute of nanoscience Delft) Date 2017-12-07 Abstract Structural maintenance of chromosome (SMC) complexes are central regulators of chromosome architecture that are essential in all domains of life. For decades, the structural biology field has been debating how these conserved protein complexes use their intricate ring-like structures to structurally organize DNA. Here, we review the contributions of single-molecule biophysical approaches to resolving the molecular mechanism of SMC protein function. To reference this document use: http://resolver.tudelft.nl/uuid:8a1740bc-20cc-4d50-bcf4-05b8d5443ef4 DOI https://doi.org/10.1038/nsmb.3507 Embargo date 2018-06-07 ISSN 1545-9985 Source Nature Structural and Molecular Biology, 24 (12), 1012-1020 Part of collection Institutional Repository Document type review Rights © 2017 J.M. Eeftens, C. Dekker Files PDF EeftensDekker_Revised_Cat ... _hoops.pdf 5.55 MB Close viewer /islandora/object/uuid:8a1740bc-20cc-4d50-bcf4-05b8d5443ef4/datastream/OBJ/view