Improving the homogeneity of brachytherapy treatment plans generated by BRIGHT using a hotspot registration method based on connected component analysis

Title

Improving the homogeneity of brachytherapy treatment plans generated by BRIGHT using a hotspot registration method based on connected component analysis

 Author

Commandeur, Joost (TU Delft Electrical Engineering, Mathematics and Computer Science)

Contributor

Bosman, P.A.N. (mentor)

Degree granting institution

Delft University of Technology

 Date

2021-11-05

 Abstract

In this thesis BRIGHT, a multi-objective evolutionary algorithm for the creation of treatment plans for high-dose rate brachytherapy for prostate cancer, is extended with a new objective to mitigate the formation of high dose contiguous volumes, i.e. hotspots. Multiple new objectives are tested on their performance to reduce hotspots, while minimally impacting existing objectives.

 Subject

brachytherapy
multi-objective optimization
Evolutionary Algorithm - EA
connected components labeling
hotspots

 To reference this document use:

http://resolver.tudelft.nl/uuid:982783be-a26c-4cb5-90ba-1e0900de9670

 Part of collection

Student theses

 Document type

master thesis

 Rights

© 2021 Joost Commandeur
Files
PDF Thesis_Joost_Commandeur_Final.pdf 32.23 MB
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