Print Email Facebook Twitter Potential applications of Zr-KIT-5: Hantzsch reaction, Meerwein–Ponndorf–Verley (MPV) reduction of 4-tert -butylcyclohexanone, and Prins reaction of citronellal Title Potential applications of Zr-KIT-5: Hantzsch reaction, Meerwein–Ponndorf–Verley (MPV) reduction of 4-tert -butylcyclohexanone, and Prins reaction of citronellal Author Vasudevan Srinivasan, V. Ranoux, A. Maheswari, R. Hanefeld, U. Ramanathan, A. Subramaniam, B. Faculty Applied Sciences Department BT/Biotechnology Date 2015-07-11 Abstract The acidity of Zr-incorporated large pore cubic mesoporous silicate, KIT-5, with Fm3m symmetry was explored as catalyst in the Hantzsch reaction for preparation of 1,4-dihydropyridine (DHP) derivatives, Meerwein–Ponndorf–Verley (MPV) reduction of 4-tert-butylcyclohexanone, and Prins reaction of citronellal. The catalyst showed ~82–94 % selectivity for formation of DHP derivatives based on substituted benzaldehydes. For the intramolecular cyclization of citronellal, the activity and isomer selectivity increased with Zr content. Both these reactions proceeded to nearly total conversion in relatively short reaction times of 3 h and 30 min, respectively. In sharp contrast, MPV reduction of 4-tert-butylcyclohexanone yielded 95 % conversion in 4 days, similar to those reported for Zr-TUD-1. Subject Zr-KIT-5Hantzsch reactionisopulegolPrins reactionMPV reduction To reference this document use: http://resolver.tudelft.nl/uuid:9853c6eb-b55b-4c4c-9e8f-5b35ac0be449 Publisher Springer ISSN 0922-6168 Source https://doi.org/10.1007/s11164-015-2157-4 Source Research on Chemical Intermediates, 42 (3), 2016 Part of collection Institutional Repository Document type journal article Rights © 2015 The Author(s)This article is published with open access at Springerlink.com Files PDF Hanefeld 2015.pdf 485.87 KB Close viewer /islandora/object/uuid:9853c6eb-b55b-4c4c-9e8f-5b35ac0be449/datastream/OBJ/view