Print Email Facebook Twitter Spin-echo small-angle neutron scattering study of the structure organization of the chromatin in biological cell Title Spin-echo small-angle neutron scattering study of the structure organization of the chromatin in biological cell Author Iashina, E.G. (Petersburg Nuclear Physics Institute (PNPI); St. Petersburg State University) Bouwman, W.G. (TU Delft RST/Neutron and Positron Methods in Materials) Duif, C.P. (TU Delft RST/Neutron and Positron Methods in Materials) Filatov, M.V. (St. Petersburg State University) Grigoriev, S. V. (Petersburg Nuclear Physics Institute (PNPI); St. Petersburg State University) Date 2017-06-20 Abstract Spin-echo small-angle scattering (SESANS) technique is a method to measure the structure of materials from nano- to micrmeter length scales. This method could be important for studying the packaging of DNA in the eukaryotic cell. We measured the SESANS function from chicken erythrocyte nuclei which is well fitted by the exponential function G(z) = exp(-z/ξ), where ξ is the correlation length of a nucleus (in experimental data ξ = 3, 3 μm). The exponential decay of G(z) corresponds to the logarithmic pair correlation function γ(r) = ln(ξ/r). As the sensitivity of the SESANS signal depends on the neutron wavelength, we propose the SESANS setup with the changeable wavelength in the range from 2 to 12 Å. Such option allows one to study in great detail the internal structure of the biological cell in the length scale from 10-2 μm to 10 μm. To reference this document use: http://resolver.tudelft.nl/uuid:a376fd3d-021b-4654-aa44-c650634e7683 DOI https://doi.org/10.1088/1742-6596/862/1/012010 ISSN 1742-6588 Source Journal of Physics: Conference Series, 862 (1) Part of collection Institutional Repository Document type journal article Rights © 2017 E.G. Iashina, W.G. Bouwman, C.P. Duif, M.V. Filatov, S. V. Grigoriev Files PDF Iashina_2017_J._Phys._3A_ ... 012010.pdf 627.37 KB Close viewer /islandora/object/uuid:a376fd3d-021b-4654-aa44-c650634e7683/datastream/OBJ/view