Comparison of frequency-domain and continuous-wave near-infrared spectroscopy devices during the immediate transition

Comparison of frequency-domain and continuous-wave near-infrared spectroscopy devices during the immediate transition

Van Essen, Tanja (Erasmus MC)
Goos, T.G. (TU Delft Medical Instruments & Bio-Inspired Technology; Erasmus MC)
Van Ballegooijen, Liza (Erasmus MC)
Pichler, Gerhard (Medical University Graz)
Urlesberger, Berndt (Medical University Graz)
Reiss, Irwin K.M. (Erasmus MC)
De Jonge, Rogier C.J. (Erasmus MC)

2020

Background: Non-invasive monitoring of cerebral tissue oxygen saturation (rcSO₂) during transition is of growing interest. Different near-infrared spectroscopy (NIRS) techniques have been developed to measure rcSO₂. We compared rcSO₂ values during the immediate transition in preterm neonates measured with frequency-domain NIRS (FD-NIRS) with those measured with continuous-wave NIRS (CW-NIRS) devices in prospective observational studies. Methods: We compared rcSO₂ values measured with an FD-NIRS device during the first 15 min after birth in neonates with a gestational age ≥ 30 weeks but < 37 weeks born at the Erasmus MC- Sophia Children's Hospital, Rotterdam, the Netherlands, with similar values measured with a CW-NIRS device in neonates born at the Medical University of Graz, Austria. Mixed models were used to adjust for repeated rcSO₂ measurements, with fixed effects for time (non-linear), device, respiratory support and the interaction of device and respiratory support with time. Additionally, parameters such as total haemoglobin concentration and oxygenated and deoxygenated haemoglobin concentrations measured by FD-NIRS were analysed. Results: Thirty-eight FD-NIRS measurements were compared with 58 CW-NIRS measurements. The FD-NIRS rcSO₂ values were consistently higher than the CW-NIRS rcSO₂ values in the first 12 min, irrespective of respiratory support. After adjustment for respiratory support, the time-dependent trend in rcSO₂ differed significantly between techniques (p < 0.01). Conclusion: As cerebral saturation measured with the FD-NIRS device differed significantly from that measured with the CW-NIRS device, differences in absolute values need to be interpreted with care. Although FD-NIRS devices have technical advantages over CW-NIRS devices, FD-NIRS devices may overestimate true cerebral oxygenation and their benefits might not outweigh the usability of the more clinically viable CW-NIRS devices.

Continuous-wave
Frequency-domain
Near-infrared spectroscopy
Preterm neonate
Transition

http://resolver.tudelft.nl/uuid:a7798ddc-e48f-4211-9e64-f4191ebca6ce

https://doi.org/10.1186/s12887-020-1987-4

BMC Pediatrics, 20 (1)

Institutional Repository

journal article

© 2020 Tanja Van Essen, T.G. Goos, Liza Van Ballegooijen, Gerhard Pichler, Berndt Urlesberger, Irwin K.M. Reiss, Rogier C.J. De Jonge