Comparison of PC-MRI and PIV measurements in an aneurysm phantom

Comparison of PC-MRI and PIV measurements in an aneurysm phantom

Guedon, A.C.P.

Dankelman, J. (mentor)
Van Bavel, E. (mentor)

Mechanical, Maritime and Materials Engineering

BioMechanical Engineering

2010-01-15

Blood flow and the associated shear forces have important biological effects on blood vessels. It has been suggested that blood flow abnormalities play a part in the development and the rupture of a deformed part of the wall of a brain artery, which is called an intracranial aneurysm, and thus in cerebral hemorrhages. Knowledge about the blood flow velocities and profiles in patient’s aneurysms is of major importance to understand their effect on the blood vessels. The Amsterdam Medical Center obtains blood flow velocities and profiles in the aneurysm region with a measurement technique called phase contrast MRI. There is a need for a validation of the measurement technique and protocol of the Amsterdam Medical Center. A common way of validation is the use of a flow phantom which is, in this case, a physical model of the circulation in the region of an aneurysm. In this project, the flow velocities and profiles in the aneurysm phantom are measured with phase contrast MRI and with Particle Image Velocimetry. The results of both measurement techniques are compared in order to contribute to the validation of blood flow measurements in intracranial aneurysms with phase contrast MRI.

aneurysm
phantom
flow
PC-MRI
PIV

http://resolver.tudelft.nl/uuid:abac5e53-0aa1-48f2-b7a2-af29d40728f5

2011-06-15

Student theses

master thesis

(c) 2010 Guedon, A.C.P.