Print Email Facebook Twitter Spectroscopic photoacoustic imaging of radiofrequency ablation in the left atrium Title Spectroscopic photoacoustic imaging of radiofrequency ablation in the left atrium Author Iskander-Rizk, Sophinese (Erasmus MC) Kruizinga, P. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC) Van Der Steen, Antonius F.W. (Erasmus MC) van Soest, G. (Erasmus MC) van der Steen, A.F.W. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC) Date 2018 Abstract Catheter-based radiofrequency ablation for atrial fibrillation has long-term success in 60-70% of cases. A better assessment of lesion quality, depth, and continuity could improve the procedure’s outcome. We investigate here photoacoustic contrast between ablated and healthy atrial-wall tissue in vitro in wavelengths spanning from 410 nm to 1000 nm. We studied single-and multi-wavelength imaging of ablation lesions and we demonstrate that a two-wavelength technique yields precise detection of lesions, achieving a diagnostic accuracy of 97%. We compare this with a best single-wavelength (640 nm) analysis that correctly identifies 82% of lesions. We discuss the origin of relevant spectroscopic features and perspectives for translation to clinical imaging. To reference this document use: http://resolver.tudelft.nl/uuid:ad9e9a2b-6f11-40b8-8393-41c6e454511e DOI https://doi.org/10.1364/BOE.9.001309 ISSN 2156-7085 Source Biomedical Optics Express, 9 (3) Part of collection Institutional Repository Document type journal article Rights © 2018 Sophinese Iskander-Rizk, P. Kruizinga, Antonius F.W. Van Der Steen, G. van Soest, A.F.W. van der Steen Files PDF boe_9_3_1309.pdf 2.52 MB Close viewer /islandora/object/uuid:ad9e9a2b-6f11-40b8-8393-41c6e454511e/datastream/OBJ/view