Print Email Facebook Twitter Deep eutectic solvents for redox biocatalysis Title Deep eutectic solvents for redox biocatalysis Author Gotor-Fernández, Vicente (Universidad de Oviedo) Paul, C.E. (TU Delft BT/Biocatalysis) Date 2019 Abstract Deep eutectic solvents (DES) are a class of neoteric solvents used in multiple applications amongst which biocatalytic processes. Due to its simple preparation, low cost and inherent biodegradable properties, its use as a non-volatile biocompatible co-solvent with both whole cells and isolated enzymes has displayed increased enzyme activity and stability translating to higher product conversions and a surprising higher enantioselectivity in a range of biotransformations. This review lays out the latest updates on the use of DES in redox biocatalytic reactions. With that purpose, a clear division has been made to summarize the application of DES in bioreduction reactions using whole cells and purified alcohol dehydrogenases, oxidations involving alcohol dehydrogenases, heme-dependent enzymes, peroxidases, laccases and catalases, ozonolysis reactions, and finally mention the application of lipase in the mediation of chemoenzymatic epoxidation and Baeyer-Villiger reactions. Subject Deep eutectic solventsNeoteric solventsNon-conventional mediaRedox biocatalysisWhole cells catalysis To reference this document use: http://resolver.tudelft.nl/uuid:c9e82552-60fb-423f-ade2-f99208dc90ae DOI https://doi.org/10.1016/j.jbiotec.2018.12.018 ISSN 0168-1656 Source Journal of Biotechnology (online), 293, 24-35 Part of collection Institutional Repository Document type review Rights © 2019 Vicente Gotor-Fernández, C.E. Paul Files PDF 1_s2.0_S0168165619300318_main.pdf 3.28 MB Close viewer /islandora/object/uuid:c9e82552-60fb-423f-ade2-f99208dc90ae/datastream/OBJ/view