Print Email Facebook Twitter Does a coupling capacitor enhance the charge balance during neural stimulation? An empirical study Title Does a coupling capacitor enhance the charge balance during neural stimulation? An empirical study Author Van Dongen, M.N. Serdijn, W.A. Faculty Electrical Engineering, Mathematics and Computer Science Department Microelectronics Date 2015-05-29 Abstract Due to their DC-blocking characteristic, coupling capacitors are widely used to prevent potentially harmful charge buildup at the electrode–tissue interface. Although the capacitors can be an effective safety measure, it often seems overlooked that coupling capacitors actually introduce an offset voltage over the electrode–tissue interface as well. This work investigates this offset voltage both analytically and experimentally. The calculations as well as the experiments using bipolar-driven platinum electrodes in a saline solution confirm that coupling capacitors introduce an offset, while they barely contribute to the passive charge balancing. In particular cases, this offset is shown to reach potentially dangerous voltage levels that could induce irreversible electrochemical reactions. This work therefore suggests that when the use of coupling capacitors is required, the offset voltage should be analyzed for all operating conditions to ensure it remains within safe boundaries. Subject electric stimulationimplantable neurostimulatorselectrodes To reference this document use: http://resolver.tudelft.nl/uuid:e06337b0-b68e-471c-82cf-0f45c7bc0234 Publisher Springer ISSN 0140-0118 Source https://doi.org/10.1007/s11517-015-1312-9 Source Medical & Biological Engineering & Computing, 2015 Part of collection Institutional Repository Document type journal article Rights (c) 2015 The Author(s)This article is published with open access at Springerlink.com Files PDF vanDongen_2015.pdf 780.81 KB Close viewer /islandora/object/uuid:e06337b0-b68e-471c-82cf-0f45c7bc0234/datastream/OBJ/view