Print Email Facebook Twitter Influence of distance and incident angle on light intensities in intravascular optical coherence tomography pullback runs Title Influence of distance and incident angle on light intensities in intravascular optical coherence tomography pullback runs Author Liu, Shengnan (Leiden University Medical Center) Eggermont, Jeroen (Leiden University Medical Center) Wolterbeek, Ron (Leiden University Medical Center) Lelieveldt, B.P.F. (TU Delft Pattern Recognition and Bioinformatics; Leiden University Medical Center) Dijkstra, J (Leiden University Medical Center) Contributor Wook Kang, Hyun (editor) Tearney, Guillermo J. (editor) Gregory, Kenton W. (editor) Marcu, Laura (editor) Skala, Melissa C. (editor) Campagnola, Paul J. (editor) Choi, Bernard (editor) Kollias, Nikiforos (editor) Zeng, Haishan (editor) Mandelis, Andreas (editor) Wong, Brian J.F. (editor) Ilgner, Justus F. (editor) Date 2016 Abstract Intravascular optical coherence tomography (IVOCT) is an intravascular imaging modality which enables the visualization arterial structures at the micro-structural level. The interpretations of these structures is mainly on the basis of relative image intensities. However, even for homogeneous tissue light intensities can differ. In this study the incident light intensity is modeled to be related to the catheter position. Two factors, the distance between catheter and inner lumen wall as well as the incident angle of the light upon the lumen wall, are considered. A three-level hierarchical model is constructed to statistically validate this model to include the potential effect of different pullbacks and/or frame numbers. The model is solved using 169 images out of 9 pull-backs recorded with a St.Jude Medical IVOCT system. F-tests results indicate that both the distance and the incident angle contribute to the model statistically significantly with p < 0.001. Based on the results from the statistical analysis, a potential compensation method is introduced to normalize the IVOCT intensities for the catheter position effects and small shadows Subject angle of incidencecatheter positioncompensationdistancehierarchical linear regressionintravascular optical coherence tomographyIVOCTstatistical analysis To reference this document use: http://resolver.tudelft.nl/uuid:e8a97eba-97da-42ff-9488-136ca84a883a DOI https://doi.org/10.1117/12.2212472 Publisher SPIE, Bellingham, WA ISBN 9781628419245 Source Proceedings of SPIE Photonic Therapeutics and Diagnostics XII Event SPIE BIOS, 2016-02-13 → 2016-02-18, San Francisco, United States Series Proceedings of SPIE, 0277-786X, 9689 Part of collection Institutional Repository Document type conference paper Rights © 2016 Shengnan Liu, Jeroen Eggermont, Ron Wolterbeek, B.P.F. Lelieveldt, J Dijkstra Files PDF 44972297_96893B.pdf 652.64 KB Close viewer /islandora/object/uuid:e8a97eba-97da-42ff-9488-136ca84a883a/datastream/OBJ/view