Print Email Facebook Twitter Hydrocarbon Synthesis via Photoenzymatic Decarboxylation of Carboxylic Acids Title Hydrocarbon Synthesis via Photoenzymatic Decarboxylation of Carboxylic Acids Author Zhang, W. (TU Delft BT/Biocatalysis) Ma, M. (TU Delft ChemE/Materials for Energy Conversion and Storage) Huijbers, M.M.E. (TU Delft BT/Biocatalysis) Filonenko, G.A. (TU Delft ChemE/Inorganic Systems Engineering) Pidko, E.A. (TU Delft ChemE/Inorganic Systems Engineering; TU Delft ChemE/Algemeen) van Schie, M.M.C.H. (TU Delft BT/Biocatalysis) de Boer, Sabrina (DECHEMA Research Institute) Smith, W.A. (TU Delft ChemE/Materials for Energy Conversion and Storage) Hollmann, F. (TU Delft BT/Biocatalysis) Date 2019 Abstract A recently discovered photodecarboxylase from Chlorella variabilis NC64A ( CvFAP) bears the promise for the efficient and selective synthesis of hydrocarbons from carboxylic acids. CvFAP, however, exhibits a clear preference for long-chain fatty acids thereby limiting its broad applicability. In this contribution, we demonstrate that the decoy molecule approach enables conversion of a broad range of carboxylic acids by filling up the vacant substrate access channel of the photodecarboxylase. These results not only demonstrate a practical application of a unique, photoactivated enzyme but also pave the way to selective production of short-chain alkanes from waste carboxylic acids under mild reaction conditions. To reference this document use: http://resolver.tudelft.nl/uuid:f94eb29d-8fdb-46d3-a040-6ff2445524e6 DOI https://doi.org/10.1021/jacs.8b12282 ISSN 0002-7863 Source Journal of the American Chemical Society, 141 (7), 3116-3120 Part of collection Institutional Repository Document type journal article Rights © 2019 W. Zhang, M. Ma, M.M.E. Huijbers, G.A. Filonenko, E.A. Pidko, M.M.C.H. van Schie, Sabrina de Boer, W.A. Smith, F. Hollmann, More Authors Files PDF jacs.8b12282.pdf 2.23 MB Close viewer /islandora/object/uuid:f94eb29d-8fdb-46d3-a040-6ff2445524e6/datastream/OBJ/view