Print Email Facebook Twitter Fast and accurate spectral-estimation axial super-resolution optical coherence tomography Title Fast and accurate spectral-estimation axial super-resolution optical coherence tomography Author de Wit, J. (TU Delft ImPhys/Computational Imaging) Angelopoulos, Kostas (University of Peloponnese) Kalkman, J. (TU Delft ImPhys/Computational Imaging) Glentis, George Othon (University of Peloponnese) Date 2021 Abstract Spectral-estimation OCT (SE-OCT) is a computational method to enhance the axial resolution beyond the traditional bandwidth limit. However, it has not yet been used widely due to its high computational load, dependency on user-optimized parameters, and inaccuracy in intensity reconstruction. In this study, we implement SE-OCT using a fast implementation of the iterative adaptive approach (IAA). This non-parametric spectral estimation method is optimized for use on OCT data. Both in simulations and experiments we show an axial resolution improvement with a factor between 2 and 10 compared to standard discrete Fourier transform. Contrary to parametric methods, IAA gives consistent peak intensity and speckle statistics. Using a recursive and fast reconstruction scheme the computation time is brought to the sub-second level for a 2D scan. Our work shows that SE-OCT can be used for volumetric OCT imaging in a reasonable computation time, thus paving the way for wide-scale implementation of superresolution OCT. Subject OA-Fund TU Delft To reference this document use: http://resolver.tudelft.nl/uuid:ff143ddc-ee8e-4947-81c3-dd0dfacd88e9 DOI https://doi.org/10.1364/OE.439761 ISSN 1094-4087 Source Optics Express, 29 (24), 39946-39966 Part of collection Institutional Repository Document type journal article Rights © 2021 J. de Wit, Kostas Angelopoulos, J. Kalkman, George Othon Glentis Files PDF oe_29_24_39946.pdf 6.5 MB Close viewer /islandora/object/uuid:ff143ddc-ee8e-4947-81c3-dd0dfacd88e9/datastream/OBJ/view