Print Email Facebook Twitter 3D printing of patient specific bioresorbable cardiovascular stents Title 3D printing of patient specific bioresorbable cardiovascular stents Author Fajardo Cortes, Jonathan (TU Delft Mechanical, Maritime and Materials Engineering) Contributor Apachitei, Julian (mentor) Zadpoor, Amir (mentor) van Leeuwen, Bas (mentor) Plettenburg, Dick (graduation committee) Degree granting institution Delft University of Technology Programme Biomedical Engineering Date 2017-08-31 Abstract Cardiovascular diseases, in particular atherosclerosis, is currently the leading cause of death worldwide with increasing numbers due to an aging population. Recently, the first bioresorbable stent (BRS), Absorb GT1 (Abbott, USA) was approved by the FDA, consequently sparking enthusiasm in BRSs and degradable polymeric biomaterials. Polymeric BRSs have been shown to be comparable to DES with the added advantage of naturally breaking down in the body within 2 years. Unfortunately, market available stents continue to offer a limited range of geometries and sizes which might not adapt to a patient’s unique lesion and vessel. Relatively a new field, additive manufacturing (AM) has been able to provide biocompatible patient specific devices for dental and orthopedic applications, resulting in a less costly and speedy recovery. However, limited developments and research exist within stents and cardiovascular applications. Thanks to the extensive research in polymeric biomaterials and their compatibility of some with AM techniques, printing of 4 mm cardiovascular stents is introduced with an Ultimaker 2+, Freeformer and Form 1+ to provide viability and printing parameter information for the printing of cardiovascular stents with PLA and PCL based biomaterials. Establishment of structural, morphological, mechanical, chemical and biodegradability characteristics with regard to material and AM technique, ideally provides a starting point for further development in the field. Subject bioresorbable stentcardiovascular stent3d printing To reference this document use: http://resolver.tudelft.nl/uuid:ad6e95ff-e466-451e-a2e9-bac2eee487d2 Embargo date 2019-08-31 Part of collection Student theses Document type master thesis Rights © 2017 Jonathan Fajardo Cortes Files PDF Thesis_Report_.pdf 9.37 MB Close viewer /islandora/object/uuid:ad6e95ff-e466-451e-a2e9-bac2eee487d2/datastream/OBJ/view