Print Email Facebook Twitter Reproducibility of the Pleth Variability Index in premature infants Title Reproducibility of the Pleth Variability Index in premature infants Author Den Boogert, Wilhelmina J. (Erasmus MC) Van Elteren, Hugo A. (Erasmus MC) Goos, T.G. (TU Delft Medical Instruments & Bio-Inspired Technology; Erasmus MC) Reiss, Irwin K.M. (Erasmus MC) De Jonge, Rogier C.J. (Erasmus MC) van Den Berg, Victor J. (Erasmus MC) Date 2017 Abstract The aim was to assess the reproducibility of the Pleth Variability Index (PVI), developed for non-invasive monitoring of peripheral perfusion, in preterm neonates below 32 weeks of gestational age. Three PVI measurements were consecutively performed in stable, comfortable preterm neonates in the first 48 h of life. On each occasion, pulse oximeter sensors were attached to two different limbs for 5 min. Reproducibility was assessed with the intra-class correlation coefficient (ICC) and Bland–Altman analysis. A total of 25 preterm neonates were included. Inter-limb comparison showed fair to moderate ICC’s with 95%-confidence intervals (95%-CI). Left hand–right hand ICC = 0.498, 95%-CI (0.119–0.753); right foot–right hand ICC = 0.314 (−0.088–0.644); right foot–left foot ICC = 0.315 (−0.089–0.628). Intra-limb comparison showed fair to moderate ICC for right foot–right foot ICC = 0.380 (−0.014–0.677); and good ICC for right hand–right hand ICC = 0.646 (0.194–0.852). Bland–Altman plots showed moderate reproducibility of measurements between different limbs and of the same limb in consecutive time periods, with large biases and wide limits of agreement. The findings from this study indicate that PVI measurement is poorly reproducible when measured on different limbs and on the same limb in stable and comfortable preterm neonates. Subject MicrocirculationPleth Variability IndexPremature neonatesReproducibility To reference this document use: http://resolver.tudelft.nl/uuid:bfe6d478-50f3-4026-a614-09fca63e09c3 DOI https://doi.org/10.1007/s10877-017-0058-3 ISSN 1387-1307 Source Journal of Clinical Monitoring and Computing, 32 (June 2018) (3), 457-464 Part of collection Institutional Repository Document type journal article Rights © 2017 Wilhelmina J. Den Boogert, Hugo A. Van Elteren, T.G. Goos, Irwin K.M. Reiss, Rogier C.J. De Jonge, Victor J. van Den Berg Files PDF 10.1007_2Fs10877_017_0058_3.pdf 941.03 KB Close viewer /islandora/object/uuid:bfe6d478-50f3-4026-a614-09fca63e09c3/datastream/OBJ/view