Simulating the operational workspace performances of fetoscopic laser photocoagulation instruments in twin-to-twin transfusion syndrome gestations

Simulating the operational workspace performances of fetoscopic laser photocoagulation instruments in twin-to-twin transfusion syndrome gestations: A preliminary empirical study

Juffermans, Joe (TU Delft Mechanical, Maritime and Materials Engineering; TU Delft Biomechanical Engineering)

van den Dobbelsteen, John (mentor)
Klumper, Frans (mentor)
de Jong, Tonke (graduation committee)
Plettenburg, Dick (graduation committee)

Delft University of Technology

Biomedical Engineering

2017-12-19

The twin-to-twin transfusion syndrome is a lethal hemodynamic imbalance between identical fetal twins as a result of vascular anastomoses in the monochorionic plate. With a fetoscopic laser photocoagulation the communicating vessels are interrupted, eliminating the inter-twin blood exchange. Since the first instruments were straight and rigid, an anterior located placenta resulted in an impaired visualization of the chorionic plate and coagulation of the vascular equator. Over the years multiple instruments have been developed to reduce these complications. However, these problems still occur within the clinic and are quoted throughout literature. In order to obtain a better understanding of the impaired visualization and decreased coagulation effectiveness, these problems in relation to the clinically aplied instruments, placenta location and the insertion path are simulated within realistic anatomical models.

TTTS
FLPC
Instruments
Intervention simulation
Anterior Placenta

http://resolver.tudelft.nl/uuid:c7c34f7c-a9b7-4ffa-aa0b-4a17a7c4389b

2018-12-19

Student theses

master thesis

© 2017 Joe Juffermans