Print Email Facebook Twitter The Rotterdam Scan Study: Design update 2016 and main findings Title The Rotterdam Scan Study: Design update 2016 and main findings Author Ikram, M.A. Van der Lugt, A. Niessen, W.J. Koudstaal, P.J. Krestin, G.P. Hofman, A. Bos, D. Vernooij, M.W. Faculty Applied Sciences Department ImPhys/Imaging Physics Date 2015-12-09 Abstract Imaging plays an essential role in research on neurological diseases in the elderly. The Rotterdam Scan Study was initiated as part of the ongoing Rotterdam Study with the aim to elucidate the causes of neurological disease by performing imaging of the brain in a prospective population-based setting. Initially, in 1995 and 1999, random subsamples of participants from the Rotterdam Study underwent neuroimaging, whereas from 2005 onwards MRI has been implemented into the core protocol of the Rotterdam Study. In this paper, we discuss the background and rationale of the Rotterdam Scan Study. Moreover, we describe the imaging protocol, image post-processing techniques, and the main findings to date. Finally, we provide recommendations for future research, which will also be topics of investigation in the Rotterdam Scan Study. Subject epidemiologypopulation-basedrisk factorsneuroimagingcohort studydementiastrokeAlzheimers diseasemicrobleedsshite matter lesionsinfarctscerebral blood flowdiffusion tensor imaginggenetics To reference this document use: http://resolver.tudelft.nl/uuid:d111f811-2970-43cc-b924-d5a80c7005bf Publisher Springer ISSN 0393-2990 Source European Journal of Epidemiology, 30 (12), 2015 Part of collection Institutional Repository Document type journal article Rights (c) 2015 The Author(s)This article is published with open access at Springerlink.com Files PDF 324746.pdf 1.55 MB Close viewer /islandora/object/uuid:d111f811-2970-43cc-b924-d5a80c7005bf/datastream/OBJ/view