Improved estimation of the temporal decay function of in vivo metabolite signals

Improved estimation of the temporal decay function of in vivo metabolite signals

Van Ormondt, D.
De Beer, R.
Van der Veen, J.W.C.
Sima, D.M.
Graveron-Demilly, D.

Applied Sciences

ImPhys/Imaging Physics

2015-03-24

MRI-scanners enable non-invasive, in vivo quantitation of metabolites in, e.g., the brain of a patient. Among other things, this requires adequate estimation of the unknown temporal decay function of the complex-valued signal emanating from the metabolites. We propose a method to render a current decay estimator more simple, accurate, and robust, and test it on a simulated signal comprising contributions from ten metabolite species and scanner noise.

metabolite quantitation
signal-decay function
semi-parametric estimation
low-pass filter

http://resolver.tudelft.nl/uuid:f7a29c18-1579-45d6-a2c2-48fe0b4f803e

ICT.Open2015

Proceedings of the The Interface for Dutch ICT-Research ProRISC, ICT.OPEN 2015: The Interface for Dutch ICT-Research, Amersfoort, The Netherlands, 24-25 March 2015

Institutional Repository

conference paper

(c) 2015 The Authors